Skip to content

Possible treatment of hereditary-hormonal hair loss by particles isolated from stem cells in the laboratory

Assessment of the effect of extracellular vesicles derived from mesenchymal stem cells in the management ofmale androgenetic alopecia: a pilot study

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240508061704N2
Enrollment
5
Registered
2024-05-30
Start date
2024-07-05
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

androgenetic alopecia. Androgenic alopecia

Interventions

Intervention group: First, the extracellular vesicles isolated from Wharton's jelly umbilical cord mesenchymal stem cells are separated and stored in phosphate buffered saline (PBS) in the freezer. It

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients with male hereditary-hormonal hair loss Patients with hair loss grade three to four Norwood-Hamilton classification

Exclusion criteria

Exclusion criteria: Patients receiving treatment for androgenetic alopecia during the last 3 months Patients receiving systematic treatment of immunosuppressive or modulating drugs in the last 3 months Patients receiving anticoagulants Patients with a history of hair transplantation Patients with a history of malignancy Patients with a history of injection phobia Patients with scalp infection or inflammation Patients with serious and uncontrolled internal diseases such as diabetes and autoimmune diseases Patients with unrealistic expectations of treatment

Design outcomes

Primary

MeasureTime frame
Increased rate of hair growth. Timepoint: A visit is done 3 months and 6 months after drug treatment. Method of measurement: Dermoscopic trichoscopy and hair count.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Keshtkar

Shiraz University of Medical Sciences

somayehkeshtkar@gmail.com+98 71 3212 5592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026