- Possible treatment of vitiligo lesions by particles isolated from stem cells in the laboratory

Investigating the effectiveness of extracellular vesicles released from mesenchymal stem cells in thetreatment of patients with persistent vitiligo lesions: a pilot study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240508061704N1

Enrollment

Registered

2024-05-25

Start date

2024-07-05

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo. Vitiligo

Interventions

First, the extracellular vesicles isolated from Wharton's jelly umbilical cord mesenchymal stem cells are separated and stored in phosphate buffered saline (PBS) in the freezer.After the patient is ad

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Patients should have stable vitiligo The patient's medical history should report the stability of the patient's disease in terms of the absence of new lesions during the last one year

Exclusion criteria

Exclusion criteria: Patients with more than 20% of the body surface involved with vitiligo pregnant women lactating women patients with skin cancer patients who have undergone other treatments for vitiligo in the past 3 months

Design outcomes

Primary

Measure	Time frame
Increase in pigment production. Timepoint: After drug treatment, monthly visits are made for up to three months, and for long-term visits after 6 months. Method of measurement: Vitiligo Area Scoring Index (VASI).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayeh Keshtkar

Shiraz University of Medical Sciences

somayehkeshtkar@gmail.com+98 71 3212 5592

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026