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Comparison of the effect of betamethasone and dexamethasone on fetal, neonatal, and maternal outcomes

Comparison of the effect of betamethasone and dexamethasone on fetal, neonatal, and maternal outcomes in pregnancies of fetus with intrauterine growth disorder

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240508061703N1
Enrollment
50
Registered
2024-05-27
Start date
2024-06-21
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory distress of newborn. Respiratory distress of newborn

Interventions

Intervention 1: Intervention group: First (after echocardiography and ultrasound of the fetus) and 24 hours after the first dose, 12 mg of betamethasone phosphate is injected intramuscularly. Interven

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Singleton pregnancy with gestational age of 26 to 34 weeks Fetus with intrauterine growth retardation Fetus with corticosteroid indication

Exclusion criteria

Exclusion criteria: Corticosteroid contraindication for the mother or her fetus Unwillingness to participate in the study

Design outcomes

Primary

MeasureTime frame
Fetus echocardiography changes. Timepoint: 3 times, 24 hours before and 24 and 48 hours after corticosteroid administration. Method of measurement: Fetus echocardiography.;Biometric and biophysical changes of the fetus. Timepoint: 3 times, 24 hours before and 24 and 48 hours after corticosteroid administration. Method of measurement: Fetus ultrasound.;Maternal glucose level. Timepoint: 3 times, 24 hours before and 24 and 48 hours after corticosteroid administration. Method of measurement: Blood sample.

Secondary

MeasureTime frame
Occurrence of neonatal complications including respiratory problems, intubation, sepsis, neonatal seizures, and neonatal hypoglycemia. Timepoint: After birth. Method of measurement: Examination and evaluation of the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehrokh Sahebdel

Tehran University of Medical Sciences

Behrokh_gbwm@yahoo.com+98 21 4216 0852

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026