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Effect of dexmedetomidine and ketamine in deep anesthesia

comparison of the effect of Dexmedetomidine and Ketamine on the depth of anesthesia in patients under neuromonitoring

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240507061698N1
Enrollment
70
Registered
2024-05-14
Start date
2024-05-30
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abnormalities of the spine. Disease of spinal cord, unspecified

Interventions

Intervention 1: Intervention group: The first group includes 35 patients who will be infused with 0.2 micrograms/kg/minute of dexmedetomidine + 0.1 micrograms/kg/minute of Remifentanil + 0.5mg/kg/hour

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age 20 to 60 years Patients with ASA CLASS 1 & 2 Patients who consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with severe heart disease Patients with severe pulmonary and respiratory problems Patients with kidney failure, fever, infection, electrolyte disorder, acid-base disorder, allergy to the studied drugs

Design outcomes

Primary

MeasureTime frame
Relaxation level. Timepoint: Before anesthesia, every 15 minutes until the end of surgery. Method of measurement: RAMSEY criterion.;Level of consciousness. Timepoint: Before anesthesia, every 15 minutes until the end of surgery. Method of measurement: bispectral index (BIS) criterion.;Vital signs. Timepoint: Before anesthesia, every 15 minutes until the end of surgery. Method of measurement: Vital signs monitor.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh mohadaseh Azizanmortazavi

Ahvaz University of Medical Sciences

mortazavi.mo@ajums.ac.ir+98 916 505 1148

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026