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Comparing the effect of Alprazolam (single dose) and Clonidine on improving the patient's stability under General Anesthesia

Comparing the effect of Alprazolam (single dose) and Clonidine on improving the patient's stability under General Anesthesia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240506061669N1
Enrollment
128
Registered
2024-06-13
Start date
2024-05-21
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic changes. Shock due to anaesthesia

Interventions

Intervention 1: Intervention group: One hour before the operation, one group receives alprazolam tablets along with 50 cc of water. Intervention 2: Intervention group: One hour before the operation, a

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Elective surgery ASA1,2 Age 18-65 years Informed consent of the patient to enter the study Non-use of drugs, alcohol, cigarettes and psychotropic drugs

Exclusion criteria

Exclusion criteria: Loss of consciousness The duration of the operation is more than 4 hours

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure. Timepoint: At the beginning of the surgery, in the middle of the surgery and at the end of the surgery, the hemodynamic status of the patients is recorded by the nurse. Method of measurement: Using operating room monitoring.;Diastolic blood pressure. Timepoint: At the beginning of the surgery, in the middle of the surgery and at the end of the surgery, the hemodynamic status of the patients is recorded by the nurse. Method of measurement: Using operating room monitoring.;Mean arterial blood pressure. Timepoint: At the beginning of the surgery, in the middle of the surgery and at the end of the surgery, the hemodynamic status of the patients is recorded by the nurse. Method of measurement: Using operating room monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Hekmati

Islamic Azad University

Hekmati.hamed@yahoo.com+98 21 2660 2642

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026