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The role of progesterone in ovulation

The role of progesterone as an ovulation trigger in IVF and IUI cycles, a clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240506061667N1
Enrollment
36
Registered
2024-05-18
Start date
2024-06-04
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility associated with anovulation

Interventions

Intervention 1: Intervention group A: 18 people will be selected in the IVF group among the patients referred to Ibn Sina infertility treatment center for egg donation who have the necessary criteria

Sponsors

Iranian academic center for education culture and research
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Patient age 20-35 years 2. Hysterosalpingography is normal in IUI group patients 3. Vaginal ultrasound is normal 4. Thyroid, prolactin, sugar and CBC tests are normal 5. AMH above 2 6. Genetic or autoimmune disease has been diagnosed

Exclusion criteria

Exclusion criteria: 1. egg donation clients whose IVF cycle is canceled due to lack of suitable follicles (10-15) 2. history of ovarian cyst and endometriosis 3. patient unwillingness 4. immune and rheumatic disease 5. sensitivity to progesterone

Design outcomes

Primary

MeasureTime frame
Primary Outcome Study of LH Surge Occurrence. Timepoint: It is at 12 and 36 hours after injection. Method of measurement: In the ultrasound before the intervention, as well as the serum level of FSH, progesterone and estrogen at 12 and 36 hours after the injection.

Secondary

MeasureTime frame
The secondary outcome is the total number of eggs obtained. Timepoint: It is at 12 and 36 hours after injection. Method of measurement: In the ultrasound before the intervention, as well as the serum level of FSH, progesterone and estrogen at 12 and 36 hours after the injection.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSimin Zafardoost

Iranian academic center for education culture and research

siminzafardoost@yahoo.com+98 21 23519

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026