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Investigation of the effect of olanzapine in patients undergoing chemotherapy

Effect of Olanzapine on appetite, nausea, and vomiting in patients undergoing chemotherapy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240505061661N1
Enrollment
180
Registered
2024-05-10
Start date
2024-05-11
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer. Secondary malignant neoplasm of unspecified site

Interventions

Intervention 1: Intervention group: olanzapine, 2.5 mg, once daily, for 12 weeks. Intervention 2: Control group: Pelacbo, 2.5 mg, once daily, for 12 weeks.

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: pregnancy

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Weight. Timepoint: Before the intervention and 12 weeks after the intervention. Method of measurement: scale.;Nausea. Timepoint: Before the intervention and 12 weeks after the intervention. Method of measurement: Interview and clinical examination.;Anorexia. Timepoint: Before the intervention and 12 weeks after the intervention. Method of measurement: Functional evaluation questionnaire for treatment of chronic anorexia nervosa.

Secondary

MeasureTime frame
C-Reactive Protein (CRP). Timepoint: Before the intervention and 12 weeks after the intervention. Method of measurement: Laboratory kit (blood test).;Albumin. Timepoint: Before the intervention and 12 weeks after the intervention. Method of measurement: Laboratory kit (blood test).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMina Norouzi

Shahid Beheshti University of Medical Sciences

noruzi2012@gmail.com+98 21 23871

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026