Adverse effects of PPIs. Hypomagnesemia
Conditions
Interventions
Intervention 1: Intervention group 1: Participants in this group received oral omeprazole 20-40 mg daily for long-term acid suppression therapy. Intervention 2: Control group: Participants in this gro
Sponsors
Pak Emirates Military Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adults =18 years of age Had an indication for long-term PPI therapy such as GERD, chronic gastritis or Zollinger Ellison syndrome and willing to participate in this study
Exclusion criteria
Exclusion criteria: Peptic ulcer disease secondary to H. pylori Medical condition that cause malabsorption (coeliac disease, chronic pancreatitis, gut resection, inflammatory bowel disease, chronic diarrhea etc) Individuals with pre-existing deficiencies or electrolytes / vitamins requiring intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Magnesium Levels. Timepoint: Baseline, 3-, 6-, 9- and 12-months. Method of measurement: Blood Sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| Calcium Levels. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood test.;Phosphate levels. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood test.;Serum iron. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood Test.;Vitamin B12 levels. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood test.;Folate levels. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood test.;Vitamin D levels. Timepoint: Baseline, 3-, 6-, 9-, 12-months. Method of measurement: Blood test. | — |
Countries
Pakistan
Contacts
Public ContactMehmood Hussain
Pak Emirates Military Hospital
Outcome results
None listed