Overactive bladder. N32.8
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: Injection of 100 units of botulinum toxin diluted with 5 cc of 0.9% normal saline into the bladder at 3 points on the posterior wall and trigone
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Overactive bladder syndrome or urge urinary incontinence Idiopathic decreased bladder compliance refractory to treatment with two or more anticholinergics
Exclusion criteria
Exclusion criteria: Previous history of botulinum toxin injection in any area of ??the body within the past 3 months Anterior, apical, and posterior compartment prolapse grade two or higher on vaginal examination based on POPQ Cognitive impairment Stress urinary incontinence, over flow, true, mixed sabagheh jarahi akhir sistam edrari dar 3_ mah gozashteh44 / 5,000History of recent urinary system surgery within the past 3 months Urinary voiding phase disorders and residual urine above 100 cc Voiding phase disorders in urodynamic study (Qmax less than 15 and pdet @Qmax less than 20 in women) Very small bladder volume below 150cc on ultrasound or VCUG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary incontinence. Timepoint: Baseline, 4, and 12 weeks after intervention. Method of measurement: ICIQ-OAB questionnaire,.;Urinary frequency. Timepoint: Baseline, 4, and 12 weeks after intervention. Method of measurement: ICIQ-OAB questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Nocturia. Timepoint: Baseline, 4, and 12 weeks after intervention. Method of measurement: ICIQ-OAB questionnaire.;Urgency. Timepoint: Baseline, 4, and 12 weeks after intervention. Method of measurement: ICIQ-OAB questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSakineh Hajebrahimi
Tabriz University of Medical Sciences
Outcome results
None listed