Condition 1: Tinnitus. Condition 2: Meniere's disease. Tinnitus Meniere's disease
Conditions
Interventions
Intervention group: 25 patients with Meniere's disease are selected using convenience sampling. Subjects are compared at baseline and after treatment. The audiometric instrument used is the Tinnitus H
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Confirming the diagnosis of Meniere's disease based on history and physical examination and audiometry Age 18 to 80 years
Exclusion criteria
Exclusion criteria: Pregnant or lactating women Diagnosis of other central or peripheral vestibular disorders, such as vestibular migraine, benign postural vertigo, paroxysmal brainstem attacks, and postural phobic vertigo. Patients with contraindications or sensitivity to betahistins, such as bronchial asthma, pheochromocytoma Treatment with other antihistamines Severe liver or kidney failure Severe coronary heart disease or heart failure, persistent uncontrolled hypertension with systolic blood pressure greater than 180 mmHg or diastolic blood pressure greater than 110 mmHg The presence of contraindications for the use of sodium valproate History of genetic disorders of the urea cycle Participating in another trial in the past 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of Tinnitus. Timepoint: At the beginning of the study (before the start of the intervention) and at the end of the intervention (3 months after the start of the intervention). Method of measurement: Audiometry and Tinnitus Handicap Inventory.;Adverse events. Timepoint: At the duration of the study and at the end of the intervention (3 months after the start of the intervention). Method of measurement: Adverse events checklist. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient satisfaction. Timepoint: At the end of the intervention (3 months after the start of the intervention). Method of measurement: Using a 3-point Likert scale (satisfied-moderate-dissatisfied). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactYalda Jabbari
Tabriz University of Medical Sciences
Outcome results
None listed