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Comparison of the effect of oral gel pilocarpine 2% and ginger 25% in patients with dry mouth after radiotherapy

Comparison of the effect of oral gel pilocarpine 2% and ginger 25% in patients with dry mouth after radiotherapy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240502061625N1
Enrollment
32
Registered
2024-06-15
Start date
2024-07-13
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia. Disturbances of salivary secretion

Interventions

Intervention 1: The first intervention group (A): ginger oral gel, ginger identified by the botanist of the faculty of pharmacy, whose herbarium code is kept in the herbarium of the faculty, is prepar
taste, appearance, etc. are used include edible grade A gelatin, glycerin to create lubricant effects, peppermint plant essence to create taste, smell and appearance, vitamin C and alpha tocopherol as
Use the salivary gland area.In order to compare the changes in the amount of saliva flow on days 1, 14 and 28, the repeated measure ANOVA between subject factor method is used, considering the type of

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: dry mouth Head and neck radiotherapy

Exclusion criteria

Exclusion criteria: alcohol consumption Iodine therapy Systemic diseases affecting the function of salivary glands (sjogren's/rheumatoid arthritis/lupus...) Hypertension Cardiovascular disease Renal disease(Edited)Restore original Parkinson,s Asthma Glaucoma Hepatitis B, C HIV COPD Using chemical/herbal drugs pregnant milking Alhergy to pilocarpine Alhergy to ginger Infection or oral lesions Tissue disorders Denture wearing Use of tobacco compounds other than cigarettes

Design outcomes

Primary

MeasureTime frame
Amount of saliva. Timepoint: Day 1 before the intervention and days 14 and 28 after the intervention. Method of measurement: Spitting test/sterile test tube.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayebeh Alipour

Islamic Azad University

alipoorsetareh@yahoo.com+98 21 2213 2234

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026