Impact of Exercise on Metabolism in Overweight/Obese Adults

Metabolic Impact of Exercise Modalities in Inactive Overweight and Obese Adults: A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240430061607N1

Enrollment

Registered

2024-06-06

Start date

2022-03-20

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: glucose intolerance. Condition 2: dyslipidemia.

Interventions

Intervention 1: Intervention group 1: Aerobic exercise training group. Participants in the AT group engaged in treadmill exercise at 50-75% of their maximum heart rate for 25-40 minutes, 3 times per w

Eligibility

Sex/Gender

Male

Age

45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Had a BMI > 24.9 kg/m2 Were aged between 45 and 60 years Volunteered to participate Were physically inactive (not achieving 30–60 min per day or 150 min per week of moderate intensity exercise or 20–60 min per day (75 min per week) of vigorous intensity and cleared a medical history form the physical activity readiness questionnaire) Were able to perform the necessary exercises

Exclusion criteria

Exclusion criteria: Any cardiovascular, respiratory, or muscle-skeletal disorders precluding physical exercise Uncontrolled hyperglycemia (= 126 mg/d) Uncontrolled hypertension (a resting blood pressure =140/100 mm hg) Active infection Acute myocardial infarction, stroke, trauma, surgery or severe liver dysfunction

Design outcomes

Primary

Measure	Time frame
Glucose tolerance. Timepoint: before intervention and at the end of eighth week. Method of measurement: GOTT tests were analyzed by the hexokinase method (COBAS, Roche), and its intracoefficient of variation ranged between 1.58% (µ=64.7 mg/dl) and 1.38% (µ=369 mg/dl).;Lipid profile. Timepoint: before intervention and at the end of eighth week. Method of measurement: An enzymatic method utilizing an Alpha X autoanalyzer with E2HL-100 kits and a sensitivity of 0.1 mmol/dL (Hitachi, Tokyo, Japan) was employed for lipid measurement.;Body composition. Timepoint: before intervention and at the end of eighth week. Method of measurement: body fat percentage were determine by abdominal, thigh, suprailiac and triceps skinfolds measurements on the right side of the body to the nearest 0.5 mm with a Lange caliper (Cambridge Scientific Instruments, Cambridge, MD, USA). and determined by sari equation.	—

Measure

Time frame

Glucose tolerance. Timepoint: before intervention and at the end of eighth week. Method of measurement: GOTT tests were analyzed by the hexokinase method (COBAS, Roche), and its intracoefficient of variation ranged between 1.58% (µ=64.7 mg/dl) and 1.38% (µ=369 mg/dl).;Lipid profile. Timepoint: before intervention and at the end of eighth week. Method of measurement: An enzymatic method utilizing an Alpha X autoanalyzer with E2HL-100 kits and a sensitivity of 0.1 mmol/dL (Hitachi, Tokyo, Japan) was employed for lipid measurement.;Body composition. Timepoint: before intervention and at the end of eighth week. Method of measurement: body fat percentage were determine by abdominal, thigh, suprailiac and triceps skinfolds measurements on the right side of the body to the nearest 0.5 mm with a Lange caliper (Cambridge Scientific Instruments, Cambridge, MD, USA). and determined by sari equation.

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Countries

Ethiopia

Contacts

Public ContactFriew Amare

Debre Markos University

firewa6070@gmail.com+251 58 771 6070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026