Skip to content

Investigating the effect of oral vitamin C supplementation and aromatherapy in type 1 complex regional pain syndrome

??????? : Comparison of the effect of oral vitamin C supplementation with Damask Rose aromatherapy on prevention of type 1 complex regional pain syndrome in limbs surgeries

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240430061602N1
Enrollment
135
Registered
2024-06-15
Start date
2024-06-09
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complex regional pain syndrome I. Complex regional pain syndrome I (CRPS I)

Interventions

Intervention 1: Intervention group: Intervention group: they will receive 500 mg of Brand Life tablets before NPO and daily from the day after surgery for 40 days. Intervention 2: Intervention group:

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Having informed consent Full consciousness of the patient Class 1 and 2 of the American Society of Anesthesiology Age over 18 years

Exclusion criteria

Exclusion criteria: Patients undergoing emergency surgeries Diabetes Smoking Drug use Anti-anxiety and sedative drugs Mental problems Infection before or after surgery History of allergy to vitamin C or Damask rose Patients with respiratory disorders that smell Damask rose causes worsening of respiratory condition Fibromyalgia History of carpal tunnel syndrome Previous history of complex regional pain syndrome History of previous organ surgery

Design outcomes

Primary

MeasureTime frame
Complex regional pain syndrome I. Timepoint: 2, 4 and 6 weeks after surgery. Method of measurement: Budapest criteria.

Secondary

MeasureTime frame
Anxiety. Timepoint: Before surgery, discharge time. Method of measurement: Spielberger anxiety questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMalihe Ranjbar Moghaddam

Mazandaran University of Medical Sciences

maliheranjbar119@gmail.com+98 992 033 5965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026