Effect of synbiotics in patients with Behcet's disease

Effect of synbiotics on disease activity and frequency of Th17 cells and Treg cells in Behcet patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240429061594N1

Enrollment

Registered

2024-05-30

Start date

2024-06-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behcet disease. Behcet's disease

Interventions

Intervention 1: Intervention group: synbiotic Patients in intervention group will take one synbiotic capsule by the name Fami Lact (including probiotic 9 10 CFU (colony-forming unit) plus prebiotics

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness to cooperate Diagnosis of Behcet's disease by rheumatologist

Exclusion criteria

Exclusion criteria: Use of nutritional supplements and antioxidant and alpha-lipoic acid during a month before the study Pregnancy and lactation History of diabetes and other chronic diseases The history of other autoimmune diseases compliance of supplemental intake less than 70% of supplement Smoking

Design outcomes

Primary

Measure	Time frame
Frequency of Th17 cells. Timepoint: Before and after intervention. Method of measurement: Flow cytometry.;Frequency of Treg cells. Timepoint: Before and after intervention. Method of measurement: Flow cytometry.;Disease activity. Timepoint: Before and after intervention. Method of measurement: Iranian BD dynamic activity measure (IBDDAM) and BD current activity form (BDCAF) scores.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Riazi

Tabriz University of Medical Sciences

nimariyazi@gmail.com+98 41 3334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026