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topical curcumin for treatment of chronic hand eczema

comparison of the safety and efficacy of topical curcumin and topical mometasone in treatment of chronic hand eczema; a randomized clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240425061563N1
Enrollment
30
Registered
2024-05-10
Start date
2024-05-21
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Hand Eczema. Other atopic dermatitis

Interventions

Intervention 1: Intervention group: the patients receive topical curcumin made by Exir Nano Sina Company of Iran. the patients will apply the medication twice daily for eight weeks on the affected are

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: patients above ?? years of age with chronic hand eczema who have not received topical or oral treatments for this condition in the past two weeks consent to participate in the study

Exclusion criteria

Exclusion criteria: patients younger than ?? years old pregnancy breastfeeding having underlying disease in need of systemic corticosteroids such as adrenal insufficiency and rheumatologic disease using topical or oral immunomodulators chronic kidney disease hepatic insufficiency the need for more potent corticosteroids (such as clobetasol) unwillingness to participate in the study

Design outcomes

Primary

MeasureTime frame
Severity of chronic hand eczema. Timepoint: 8 weeks after treatment initiation. Method of measurement: Hand Eczema Severity Index (HECSI).

Secondary

MeasureTime frame
Adverse effects of topical curcumin. Timepoint: 8 weeks from initiation of therapy. Method of measurement: interview and physical examination.;Quality of lfe. Timepoint: 8 weeks from initiation of therapy. Method of measurement: Dermatologic Life Quality Index (DLQI).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Khajavi

Shiraz University of Medical Sciences

dr.elhamkhajavi@gmail.com+98 71 3230 5884

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026