The Effect of Combined Exercise and Curcumin Supplementation in Hemodialysis Disease

The Effect of 12 Weeks of Combined Exercise During Dialysis With Curcumin Supplementation on Serum Sclerostin Concentration and MGP Protein in Hemodialysis Disease

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240420061528N1

Enrollment

Registered

2025-07-19

Start date

2025-06-04

Completion date

Unknown

Last updated

2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dialysis disease.

Interventions

Intervention 1: Intervention group: exercise, After the initial assessments mentioned earlier, the exercise group participated in a combined exercise program aligned with the dialysis schedule, consi

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Chronic kidney disease Hemodialysis disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The Effect of 12 Weeks of Combined Exercise During Dialysis With Curcumin Supplementation on Serum Sclerostin Concentration and MGP Protein in Hemodialysis Disease. Timepoint: To measure the effect of 12 weeks of combined exercises during dialysis with curcumin supplementation on serum concentrations of sclerostin and MGP protein, blood samples were collected in two stages at the beginning of the dialysis session (before the exercise period, and after the end of 12 weeks of exercise). Method of measurement: Serum MGP and sclerostin factors were measured by ELISA.	—

Measure

Time frame

The Effect of 12 Weeks of Combined Exercise During Dialysis With Curcumin Supplementation on Serum Sclerostin Concentration and MGP Protein in Hemodialysis Disease. Timepoint: To measure the effect of 12 weeks of combined exercises during dialysis with curcumin supplementation on serum concentrations of sclerostin and MGP protein, blood samples were collected in two stages at the beginning of the dialysis session (before the exercise period, and after the end of 12 weeks of exercise). Method of measurement: Serum MGP and sclerostin factors were measured by ELISA.

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Secondary

Measure	Time frame
The Effect of 12 Weeks of Combined Exercise During Dialysis With Curcumin Supplementation on Serum Sclerostin Concentration and MGP Protein in Hemodialysis Disease. Timepoint: Blood samples were collected in two stages at the beginning of the dialysis session (before the training period, and after the end of 12 weeks of training) and serum MGP and sclerostin factors were measured. Method of measurement: Serum MGP and sclerostin factors were measured by ELISA.	—

Measure

Time frame

The Effect of 12 Weeks of Combined Exercise During Dialysis With Curcumin Supplementation on Serum Sclerostin Concentration and MGP Protein in Hemodialysis Disease. Timepoint: Blood samples were collected in two stages at the beginning of the dialysis session (before the training period, and after the end of 12 weeks of training) and serum MGP and sclerostin factors were measured. Method of measurement: Serum MGP and sclerostin factors were measured by ELISA.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactRogayeh Fakhrpour

The University of Shahid Madani Azarbaijan

Fakhrpour@azaruniv.ac.ir+98 914 301 0136

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026