Eosinophilic gastroenteritis. Eosinophilic gastritis or gastroenteritis
Conditions
Interventions
Intervention 1: Intervention group: PPI and probiotic recipients (one daily Prokid capsule). Intervention 2: Control group: PPI and placebo.
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 15 Years
Inclusion criteria
Inclusion criteria: Definitive diagnosis of eosinophilic gastritis based on the following diagnostic criteria In pathological view =30 Eo/HPF in =5 HPF or =70 Eo/HPF in =3 HPF (stomach) =52 Eo/HPF (duodenum) =56 Eo/HPF (ileum) In endoscopic view: micronodules, erogenous and mucosal hyperemia Parents' consent to participate in the study
Exclusion criteria
Exclusion criteria: Non-compliance with the patient's medication Incompleteness of information Cortone/PPI/antibiotics use Patients with immune deficiency Other eosinophilic diseases such as IBD, celiac disease, parasitic diseases and Crohn's disease Cases of disturbed thyroid tests that require treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improving digestive symptoms (abdominal pain, diarrhea, nausea and vomiting, and constipation). Timepoint: At the beginning of the study and 10 weeks after the start of treatment. Method of measurement: Check clinical symptoms by asking the patient and family.;The recovery rate in the endoscopic view (number of micronodules, number of erogenous and mucosal hyperemia). Timepoint: At the beginning of the study and 10 weeks after the start of treatment. Method of measurement: Based on endoscopy and gastroenterologist diagnosis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKambiz Eftekharian
Tehran University of Medical Sciences
Outcome results
None listed