The effect of vitamins D and C in the prevention of complex regional pain syndrome in extra-articular distal radius fractures

Effect of vitamin D and C in preventing complex regional pain syndrome (CRPS) in distal extra-articular radius fractures in patients aged 40 to 70 years.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240416061506N1

Enrollment

250

Registered

2024-06-01

Start date

2024-05-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extra-articular distal radius fractures. Fracture of lower end of radius

Interventions

Intervention 1: Intervention group 1: 1000 mg of vitamin D daily. Intervention 2: Intervention group 2: 1000 mg of vitamin D and 500 mg of vitamin C daily. Intervention 3: Control group: 500 mg of vit

Eligibility

Sex/Gender

All

Age

40 Years to 70 Years

Inclusion criteria

Inclusion criteria: People with distal radius fracture Age 40 to 70

Exclusion criteria

Exclusion criteria: History of disorders in vitamin D metabolism history of multiple fractures History of previous distal radius fracture History of autoimmune disease History of open fracture

Design outcomes

Primary

Measure	Time frame
Complex Regional Pain Syndrome. Timepoint: The cause of trauma to the distal radius, type of treatment, and type of extra-articular fracture will be recorded. The patients will be evaluated 4, 8, and 12 weeks after the treatment in terms of symptoms of complex regional pain syndrome. Method of measurement: Clinical examination and numerical pain rating scale (NPRS) questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Reza Sadeghi Far

Kerman University of Medical Sciences

sadeghifar@kmu.ac.ir+98 34 3223 5011

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026