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Investigating the effect of Methylphenidate (Ritalin) on the level of consciousness of patients with traumatic brain injury in Imam Khomeini Hospital of Urmia

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240415061495N1
Enrollment
962
Registered
2024-04-20
Start date
2024-04-16
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury. Diffuse traumatic brain injury

Interventions

Intervention 1: Intervention group: Ritalin drug (methylphenidate hydrochloride) which is 10 mg orally three times a day starting from the third day of hospitalization and the patients GCS is measured

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with traumatic brain injury were between 15 and 60 years old GCS between 7 and 11 intubation No history of brain damage, seizures, high blood pressure, ischemic heart disease and diabetes No addiction to psychedelics and narcotics or Amphetamine use Heart rate less than 120 beats per minute

Exclusion criteria

Exclusion criteria: Evidence of drug allergy Patients who could not tolerate enteral feeding despite maximal medical treatment in the first 48 hours of admission

Design outcomes

Primary

MeasureTime frame
GCS SCORE. Timepoint: The third day after receiving the medicine on a daily basis. Method of measurement: GCS score table.;APACHE II score. Timepoint: rom the third day of hospitalization, starting with Ritalin - daily. Method of measurement: APACHE II Table.

Secondary

MeasureTime frame
Length of hospitalization of patients. Timepoint: From the first day until discharge from the hospital. Method of measurement: Number of days of hospitalization.;Patient extubation time. Timepoint: From the time of hospitalization and intubation until the patient is extubated. Method of measurement: Duration of extubation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Tariverdi

Oroumia University of Medical Sciences

Tariverdialireza@gmail.com+98 44 3383 8410

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026