A Multiple Intervention on Adult Patients

The Effect of a Multimodal Interventions on the Quality of Life, Physical Performance and Body Composition of Adult Patients with Cachexia Caused by Gastric and Esophageal Cancer: a Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240406061430N1

Enrollment

Registered

2024-05-05

Start date

2024-05-21

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cachexia caused by gastric and esophagus cancer.

Interventions

Intervention 1: In addition to their usual treatment, they will receive resistance training with exercise bands, a Mediterranean diet, a prescription for 150 minutes of low-to-moderate aerobic exercis

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with Gastric and Esophageal Cancer 2. Patients with Cachexia 3. Successful Eligibility for First-Line Radiotherapy or Chemotherapy Guidelines 4. Patients' Treatment Process must be Complete 5. Karnofsky Functional Status at least 70% 6. Nutritional Drugs 7. Patients without Uncontrolled Acute Underlying Diseases, Kidney Failure, Disease, Acquired Immunodeficiency Syndrome, Intestinal Diseases or Chronic Disease Treatments that Cause Cachexia Related to the Disease 8. Male and Female Patients 18 years and Older 9. Willing Patients To Participate in the Study 10. Having a Doctor's Permission to Participate in Diet and Exercise 11.Having Online Classes.

Exclusion criteria

Exclusion criteria: 1. Patients Who Die 2. Patients Who Comply with Less than 60% of the Recommended Nutrition 3. Changing the Route of Oral Nutrition to Enteral or Intravenous Nutrition 4. Reluctance to Continue the Study 5. Changing the Treatment Protocol 6. Major Surgery in the Last 4 Weeks .

Design outcomes

Primary

Measure	Time frame
Mediterranean Diet. Timepoint: Before and After. Method of measurement: PG-SGA Nutritional Status Questionnaire.;Quality of Life. Timepoint: Before and After. Method of measurement: EOPTC-QLQ-C30 Quality of Life Questionnaire.;Tiredness. Timepoint: Before and After. Method of measurement: FSS Fatigue Intensity Questionnaire.;Physical Performance. Timepoint: Before and After. Method of measurement: Getting up and Sitting for 30 Seconds.;Upper Limb Muscle Strength. Timepoint: Before and After. Method of measurement: 5 Repetition Maximum Chest Press Test.;Lower Limb Muscle Strength. Timepoint: Before and After. Method of measurement: 5 Repetition Maximum Leg Press Test.;Body Fat Percentage. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.;Visceral Fat. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.;Muscle Mass. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.	—

Measure

Time frame

Mediterranean Diet. Timepoint: Before and After. Method of measurement: PG-SGA Nutritional Status Questionnaire.;Quality of Life. Timepoint: Before and After. Method of measurement: EOPTC-QLQ-C30 Quality of Life Questionnaire.;Tiredness. Timepoint: Before and After. Method of measurement: FSS Fatigue Intensity Questionnaire.;Physical Performance. Timepoint: Before and After. Method of measurement: Getting up and Sitting for 30 Seconds.;Upper Limb Muscle Strength. Timepoint: Before and After. Method of measurement: 5 Repetition Maximum Chest Press Test.;Lower Limb Muscle Strength. Timepoint: Before and After. Method of measurement: 5 Repetition Maximum Leg Press Test.;Body Fat Percentage. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.;Visceral Fat. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.;Muscle Mass. Timepoint: Before and After. Method of measurement: Abdominal CT Scan Without Contrast.

—

Secondary

Measure	Time frame
Mediterranean Diet. Timepoint: Before and After. Method of measurement: FFQ Food Frequency Questionnaire.;Mediterranean Diet. Timepoint: The Second, Fourth, Sixth and Eighth Week of Study. Method of measurement: 24-Hour Food Reminder Questionnaire.;Quality of Life. Timepoint: Before and After. Method of measurement: Sharkey Physical Activity Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Faraji Sefidkhani

Shahed University

faraji4156@gmail.com+98 21 3358 7143

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026