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Investigating and comparing the effect of combined herbal mouthwash (containing thyme, mord, licorice and aloe vera) and nystatin on Denture stomatitis

Investigating and comparing the effect of combined herbal mouthwash (containing thyme, mord, licorice and aloe vera) and nystatin on Denture stomatitis; A three-blind randomized clinical trial study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240406061421N1
Enrollment
48
Registered
2024-04-15
Start date
2024-04-15
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis.

Interventions

Intervention 1: Intervention group: patients who receive herbal mouthwash. Intervention 2: Control group: patients receiving nystatin.

Sponsors

Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to No maximum

Inclusion criteria

Inclusion criteria: People who volunteer to participate in the study Patients with denture stomatitis lesions in the active phase (diagnostic criteria are swelling and inflammation below the surface of the prosthesis) who are clinically confirmed by two specialists in oral diseases.

Exclusion criteria

Exclusion criteria: Improper prosthesis Suffering from systemic and autoimmune diseases such as diabetes, blood pressure, etc. The patients' use of any type of medicine that affects the quality and quantity of saliva

Design outcomes

Primary

MeasureTime frame
Dimensions of the lesion. Timepoint: The first, seventh and fourteenth days from the time of entering the study. Method of measurement: Caliper in mm.

Secondary

MeasureTime frame
Burning and pain. Timepoint: The first, seventh and fourteenth days from the time of entering the study. Method of measurement: VAS.;Pain. Timepoint: The first, seventh and fourteenth days from the time of entering the study. Method of measurement: VAS.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Rahmani

Qazvin University of Medical Sciences

hanierahmani7@gmail.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026