Effect of Mouthwash after SRP on MMP-8 factor

Comparison of the effect of using chlorhexidine and Listerine mouthwash after Scaling and Root Planning(SRP) on Matrix metalloproteinase_8(MMP-8) salivary factor and periodontal indexes in gingivitis patients.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240405061414N1

Enrollment

Registered

2024-08-08

Start date

2024-08-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis. Gingivitis and periodontal diseases

Interventions

Intervention 1: Intervention group:. Intervention 2: Control group:.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Older than 18 years old Signs and Clinical symptoms of gingivitis Full mouth plaque index(FMPI) higher up 20 percent Full mouth bleeding index(FMBI) higher up 20 percent

Exclusion criteria

Exclusion criteria: Diabetes Cigarette Smoker Steroid User Pregnancy and lactation Present of periodontitis with probing depth(PD) upper than 3mm Present of periodontitis with Clinical attachment loss(CAL) upper than 2mm in proximal Present of implant Present of veneer and laminate Present of crown and pontic

Design outcomes

Primary

Measure	Time frame
Level of MMP-8 salivary factor. Timepoint: Before and one month later dental procedure. Method of measurement: Eliza kite.	—

Secondary

Measure	Time frame
Bleeding on probing. Timepoint: before and one month later dental procedure. Method of measurement: Bleeding Point Index.;Plaque Index. Timepoint: before and one month later dental procedure. Method of measurement: Leo and Silness index.;Gingival Index. Timepoint: before and one month later dental procedure. Method of measurement: Leo and Silness index.;Clinical attachment loss. Timepoint: before and one month later dental procedure. Method of measurement: The distance between the CEJ and the depth of the pocket was measured using a periodontal probe at six surface.;Probing depth. Timepoint: before and one month later dental procedure. Method of measurement: The distance from the gingival margin to the junctional epithelium was measured by the periodontal probe in these six levels.	—

Measure

Time frame

Bleeding on probing. Timepoint: before and one month later dental procedure. Method of measurement: Bleeding Point Index.;Plaque Index. Timepoint: before and one month later dental procedure. Method of measurement: Leo and Silness index.;Gingival Index. Timepoint: before and one month later dental procedure. Method of measurement: Leo and Silness index.;Clinical attachment loss. Timepoint: before and one month later dental procedure. Method of measurement: The distance between the CEJ and the depth of the pocket was measured using a periodontal probe at six surface.;Probing depth. Timepoint: before and one month later dental procedure. Method of measurement: The distance from the gingival margin to the junctional epithelium was measured by the periodontal probe in these six levels.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Taghizadeh

Ghoum University of Medical Sciences

bendettahosein@gmail.com+98 25 3887 0301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026