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A comparative study of the effect of intravenous administration of ketorolac and acetaminophen on pain relief after Uvulopalatopharyngoplasty surgery

A comparative study of the effect of intravenous administration of ketorolac and acetaminophen on pain relief after Uvulopalatopharyngoplasty surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240402061399N1
Enrollment
60
Registered
2024-04-09
Start date
2024-04-20
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uvulopalatopharyngoplasty.

Interventions

Intervention group: 0.5 mg/kg (maximum dose 30 mg) intravenous ketorolac half an hour before the end of surgery and then every 8 hours until 24 hours after surgery.

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: patient with american society of anesthesiologists physical status classification(ASA) BMI?35

Exclusion criteria

Exclusion criteria: heart disease uncontrolled hypertension uncontrolled diabetes gastrointestinal disease, Gastroesophageal reflux disease (GERD) Patient non-cooperation anti coagulant usage drug abuse corticosteroid usage renal disease surgery time more than 2 hr

Design outcomes

Primary

MeasureTime frame
Pain intensity, need for narcotics, time to start swallowing liquids, time to start swallowing solids. Timepoint: Number of times the need for narcotics during the first 48 hours after surgery, time to start swallowing liquids and solids, pain intensity 6, 12, 24 and 48 hours after surgery. Method of measurement: Pain intensity based on Visual Analogue Scalescale, number of times the need for narcotics, time to start swallowing liquids and solids.

Secondary

MeasureTime frame
Heart rate, blood pressure, slow bleeding, nausea, vomiting, rash, dizziness. Timepoint: Heart rate and blood pressure before and after induction of anesthesia, after extubation, 0, 15 and 60 minutes into recovery. Bleeding in the first 48 hours after surgery. Nausea, vomiting, rash and dizziness in the first 24 hours after surgery. Method of measurement: Heart rate per minute, blood pressure mm Hg. Bleeding, nausea and vomiting, rash and dizziness or not.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmaryam bahaloo

Yazd University of Medical Sciences

drbahaloo@gmail.com+98 35 3826 9200

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026