dry mouth.
Conditions
Interventions
Intervention 1: Intervention group: Taking oral pilocarpine spray. Intervention 2: Intervention group: Taking nasal pilocarpine spray. Intervention 3: Control group: nasal stealed water spray.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Head and neck cancer incidence based on pathological evidence and diagnosis by an otolaryngologist Receiving radiotherapy treatment with a minimum regimen of 60 Gy
Exclusion criteria
Exclusion criteria: Concomitant use of tricyclic antidepressants Taking antihistamines with anticholinergic properties Having cardiovascular, renal, pulmonary, ocular, or other chronic diseases that could affect the evaluation of pilocarpine's efficacy Concomitant administration of beta-blockers or pilocarpine with ophthalmological indications Patient's unwillingness to participate in the study History of sensitivity to pilocarpine or occurrence of hypersensitivity reactions after initiation of treatment Lack of access to the patient after the study began
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Dry Mouth Score (CODE). Timepoint: zero and 2 week. Method of measurement: Clinical Dry Mouth Score (CODE). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAfrooz Eshaghian
Esfahan University of Medical Sciences
Outcome results
None listed