The effect of Gabapentin in improving pain and mouth opening after extraction of mandibular third molar

Examining the use of Gabapentin orally and Dexamethasone by injection before surgery in improving pain and maximum mouth opening after mandibular impacted third molar surgery.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240319061334N1

Enrollment

Registered

2024-09-15

Start date

2024-10-06

Completion date

Unknown

Last updated

2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain and maximum mouth opening.

Interventions

Intervention 1: Intervention group: Gabapentin with Dexamethasone. Intervention 2: Control group: Dexamethasone.

Eligibility

Sex/Gender

All

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Full impacted mandibular third molars in both arches

Exclusion criteria

Exclusion criteria: Systemic problems Radiotherapy Diabetes Bleeding problems Taking Bisphosphonate drugs for a long time

Design outcomes

Primary

Measure	Time frame
Amount of pain based on visual analogue scale. Timepoint: 2, 4, 12, 24, 72 hours after surgery. Method of measurement: Pain based on visual analogue scale.;Mouth opening based on maximum mouth opening. Timepoint: 3 days after surgery. Method of measurement: Distance between incisal edge of lower and upper incisors with caliper graduated.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactfarhad nurvash

Islamic Azad University

Kananghaffariasl@gmail.com+98 21 2272 7522

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026