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Magnesium in pain control

A comparison of intravenous magnesium sulfate plus ketamine versus intravenous ketamine alone for acute pain control in long bone fractures

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240318061327N1
Enrollment
180
Registered
2024-05-31
Start date
2024-06-04
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Long bone fracture. Condition 2: Investigating the analgesic effect of ketamine. Condition 3: Investigating the analgesic effect of magnesium sulfate + ketamine.

Interventions

Intervention 1: Control group: ketamine alone with a dose of 0.3 mg/kg until the sample volume is 20 cc of normal saline, diluted and received as a bolus after registering the vas scoring at zero minu

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: All patients with long bone fractures aged 18 to 65 years and weighing between 60 to 80 kg and with a vas scoring pain level of more than 4 out of 10 have referred to the Golestan hospital emergency room, and there was no pain relief intervention before that, including the prescription of any medication. have not had

Exclusion criteria

Exclusion criteria: Unstable hemodynamics, alcohol consumption, neuromuscular diseases, pregnant and lactating women, high blood pressure (systolic more than 145 mmHg and diastolic more than 100 mmHg), history of benzodiazepine and ketamine use, medical diseases (such as heart failure, liver, kidney, stomach ulcer, cardiac arrhythmia).

Design outcomes

Primary

MeasureTime frame
Numerical scale of pain intensity. Timepoint: Upon arrival (0) and 5, 15 and 30 minutes. Method of measurement: visual analog scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHassan Motamed

Ahvaz University of Medical Sciences

motamed-h@ajums.ac.ir+98 61 3374 3009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026