Patients undergoing complex cardiac surgery. Mechanical complication of coronary artery bypass graft and biological heart valve graft
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: Group A: 60 pulses per minute, the rest of the settings are the same and are as follows: 30% Base Flow and Pulse Width by default 40% but accord
Sponsors
Rajaee heart center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients conscious satisfaction Age range of 18 to 75 Patients undergoing elective complex surgery on CPB Patients with 30% = Ejection fraction Having no history of heart surgery Having no liver dysfunction AST>140 unite / L and ALT>40 unite / L and no lung dysfunction like FEV1>65% CR10 Having no active inflammation since 1 month ago Not using antioxidant and anti inflammatory drugs since 1 month ago
Exclusion criteria
Exclusion criteria: Aortic cross clamp time <20 min Pulse pressure <20 mmhg Redo surgeries Emergency surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Examination of malondialdehyde at specified times. Timepoint: Preoperatively, immediately after bypass, 24 hours later in the intensive care unit. Method of measurement: Blood test.;Total antioxidant capacity. Timepoint: Preoperatively, immediately after bypass, 24 hours later in the intensive care unit. Method of measurement: Blood test.;Lactat. Timepoint: Preoperatively, immediately after bypass, 24 hours later in the intensive care unit. Method of measurement: Blood test. | — |
Secondary
| Measure | Time frame |
|---|---|
| ICU stay. Timepoint: Post operative. Method of measurement: patients file.;Ventilation time. Timepoint: Post operative. Method of measurement: Patients file.;Reducing mortality and morbidity. Timepoint: Post operative. Method of measurement: patients file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArezoo Moradi
Rajaee heart center
Outcome results
None listed