Postbiotic Mouthwash In Acute Leukemia

Investigating Effect Of Postbiotic Mouthwash On Mucositis Caused by Chemotherapy In Patients With Acute Leukemia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240313061280N2

Enrollment

Registered

2024-11-09

Start date

2024-11-21

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Mucositis Due To Chemotherapy. Oral mucositis (ulcerative) due to antineoplastic therapy

Interventions

Intervention 1: Intervention group: synbiotic lysate mouthwash containing two strains of Lactobacillus plantarum and Lactobacillus johnsoni - they gargle the mouthwash three times a day and each time

Eligibility

Sex/Gender

All

Age

7 Years to 18 Years

Inclusion criteria

Inclusion criteria: Acute Leukemia Patients In Induction Phase of Treatment

Exclusion criteria

Exclusion criteria: If Patients Does Not Want to Continue Trails, After Documenting The Reason, They Will Exclude. If, For Any Reason, The Mouthwash Is Not Used In More Than 20% of Days.

Design outcomes

Primary

Measure	Time frame
Oral Mucositis (any severity with WHO grading). Timepoint: Before Intervention, Then Weekly up to the End of Induction Therapy. Method of measurement: WHO grading scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Moazzen

Mashhad University of Medical Sciences

moazzenn@mums.ac.ir+98 51 3879 5031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026