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Investigating the Effect of MIND Diet with Restricted Calories and Probiotic Supplement on Fertility in Overweight and Obese Males

Investigating the Effects of MIND Diet with Restricted Calories and Probiotic Supplement on Fertility, Sexual Performance and Quality of Sexual Life in Overweight and Obese Males

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240313061277N1
Enrollment
84
Registered
2024-03-31
Start date
2024-05-04
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity and overweight. Obesity due to excess calories

Interventions

Intervention 1: The first intervention group: the group receiving MIND diet with restricted calories + probiotic supplement for 3 months. To adjust the diet, the energy needed by the person is obtaine

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Having informed consent Married adult men Ages 20-45 years Overweight and obese men with a body mass index greater than 25 Not using probiotic supplements in the last 3 months

Exclusion criteria

Exclusion criteria: Suffering from Azoospermia Having a Varicocele Suffering from Cryptorchidism Suffering from Microorchidism History of Vasectomy Men taking drugs that harm spermatogenesis such as sulfasalazine Men with tobacco, alcohol or drug use Getting infections and anatomical abnormalities of the genital system Suffering from cancer and chronic diseases

Design outcomes

Primary

MeasureTime frame
Semen parameters (concentration, motility, percentage of live sperm, morphology, sperm DNA fragmentation index). Timepoint: Before and 3 months after the intervention. Method of measurement: Light microscope with 1000x magnification will be used to calculate movement, number of live sperm and morphology.;Serum levels of androgens (total testosterone, free testosterone, dihydroepiandrosterone). Timepoint: Before and 3 months after the intervention. Method of measurement: by ELISA method by monobind kits.;Sexual performance score. Timepoint: Before and 3 months after the intervention. Method of measurement: Male sexual performance questionnaire.;Sex life quality score. Timepoint: Before and 3 months after the intervention. Method of measurement: Men's Sexual Quality of Life Questionnaire: SQOL-M.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Shamsi-goushki

Mashhad University of Medical Sciences

Shamsia4001@mums.ac.ir+98 51 3882 7034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jul 15, 2026