Overweight and obesity. Overweight and obesity
Conditions
Interventions
Intervention 1: Intervention group: He receives an intragastric botulinum toxin injection under endoscopic guidance. Patients in the intervention arm will receive 5 cc containing 500 units of botulinu
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Body mass index (BMI) >27 kg/m2 and more Botulinum toxin injection candidate
Exclusion criteria
Exclusion criteria: history of previous bariatric surgery Known allergy to any ingredients in Masport or allergic reaction to any other botulinum toxin product Known allergy to any ingredients in Liraglutide Pregnancy or lactation Known pre-existing neuromuscular disorders or peripheral motor neuropathic disease (e.g. amyotrophic lateral sclerosis, motor neuropathy) Patients with known liver cirrhosis or known esophageal/gastric varices Known eating disorders Known alcohol or drug abuse
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Height to weight ratio formula.;Waist circumference. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Meter.;Hip circumference. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Meter.;Waist to hip ratio. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: The formula for the ratio of waist circumference to hips.;Arm circumference. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Meter.;Lipid profile. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Laboratory kits.;Blood glucose. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Laboratory kits. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: Before the intervention, one month, three months and six months after the intervention. Method of measurement: Patient examination and history.;Patient satisfaction of intervention. Timepoint: Six months after the intervention. Method of measurement: Questionnaire of satisfaction with weight loss program. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGolnar Gohardehi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed