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The effect of Basil on vaginal atrophy

The effect of using ocimum basilicum vaginal cream compared to placebo on vaginal atrophy in menopausal women: A randomized clinical trial study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240311061257N1
Enrollment
60
Registered
2024-04-05
Start date
2024-05-04
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal atrophy. Postmenopausal atrophic vaginitis

Interventions

Intervention 1: Intervention group: Basil vaginal cream 5%, manufactured in the Pharmacology of Medicinal Plants Department at Mashhad University of Medical Sciences. It will be used for 8 weeks, with

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
45 Years to 60 Years

Inclusion criteria

Inclusion criteria: Being Iranian and residing in Rasht Satisfaction with participating in the study Body mass index less than 30 Reading and writing literacy Married and having had sexual activity in the past 6 months Natural menopause Aged 45-60 years Normal pap smear Diagnosis of vaginal atrophy

Exclusion criteria

Exclusion criteria: Using phytoestrogens one month before the start of the study Hormone therapy in the past 6 months before the start of the study Abnormal vaginal bleeding Specific medical conditions Use of specific medications Vaginal infections History of cancer and estrogen-related diseases History of severe anxiety and depression Sensitivity to basil Visit due to complaints of vaginal atrophy and request for treatment

Design outcomes

Primary

MeasureTime frame
Mental symptoms of vaginal atrophy. Timepoint: Before the study, and 8 weeks after the intervention. Method of measurement: Vaginal assessment scale.;Vaginal PH. Timepoint: Before the study, and 8 weeks after the intervention. Method of measurement: PH-indicator strips.;Vaginal maturation index. Timepoint: Before the study, and 8 weeks after the intervention. Method of measurement: Pathological examination.;Vaginal maturation value. Timepoint: Before the study, and 8 weeks after the intervention. Method of measurement: Pathological examination.

Countries

Iran (Islamic Republic of)

Contacts

Public Contact????? ???? ???????

Mashhad University of Medical Sciences

razavisf4012@mums.ac.ir+98 51 3859 1511

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026