The Effects of Exercise Training with supplementation

The effect of high-intensity interval training and coQ10 supplementation on some physiological markers and inflammatory markers in older adults

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240310061243N1

Enrollment

Registered

2024-07-25

Start date

2024-07-31

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ageing.

Interventions

Intervention 1: Intervention group: High-intensity interval training with Q10 supplementation. Intervention 2: Control group: High-intensity interval training with a placebo consumption.

Eligibility

Sex/Gender

All

Age

65 Years to 75 Years

Inclusion criteria

Inclusion criteria: Ability to walk independently based on Timed Up and Go (TUG) tests and 25-foot walk Age range of 65 to 75 years Non-participation in sports programs from 6 months before intervention

Exclusion criteria

Exclusion criteria: Consumption of any dietary supplement other than the specified supplement Having any orthopedic issues in the lower body Prohibition from participating in sports activities by a doctor Suffering from cardiovascular and respiratory diseases

Design outcomes

Primary

Measure	Time frame
Antioxidant status. Timepoint: Before starting and after the end of the intervention (pretest and post-test). Method of measurement: Glutathione peroxidase, superoxide dismutase, malondialdehyde, total antioxidant capacity research kits.;CRP as an inflammatory marker. Timepoint: Before starting and after the end of the intervention. Method of measurement: Quantitative CRP Diagnostic Kit.;Liver enzymes ALT and AST. Timepoint: Before starting and after the end of the intervention. Method of measurement: Diagnostic kit.;Body fat percentage and lean body mass. Timepoint: Before starting and after the end of the intervention. Method of measurement: Body composition.;Physical performance (balance, walking speed, aerobic capacity, lower and upper body strength). Timepoint: Before starting and after the end of the intervention. Method of measurement: Timed Up and Go test, 25-foot walking, 10-meter walking, 6 min walk test, chair stand test, Astrand Cycle Ergometer Test, Hand grip.	—

Measure

Time frame

Antioxidant status. Timepoint: Before starting and after the end of the intervention (pretest and post-test). Method of measurement: Glutathione peroxidase, superoxide dismutase, malondialdehyde, total antioxidant capacity research kits.;CRP as an inflammatory marker. Timepoint: Before starting and after the end of the intervention. Method of measurement: Quantitative CRP Diagnostic Kit.;Liver enzymes ALT and AST. Timepoint: Before starting and after the end of the intervention. Method of measurement: Diagnostic kit.;Body fat percentage and lean body mass. Timepoint: Before starting and after the end of the intervention. Method of measurement: Body composition.;Physical performance (balance, walking speed, aerobic capacity, lower and upper body strength). Timepoint: Before starting and after the end of the intervention. Method of measurement: Timed Up and Go test, 25-foot walking, 10-meter walking, 6 min walk test, chair stand test, Astrand Cycle Ergometer Test, Hand grip.

—

Secondary

Measure	Time frame
Sleep quality. Timepoint: Before and after the intervention. Method of measurement: Pittsburgh Sleep Quality Index.;Quality of Life. Timepoint: Before and after the intervention. Method of measurement: Older People's Quality of Life Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Kargar Fard

The University of Isfahan

kargar_m46@yahoo.com+98 31 3793 4282

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026