Effectiveness of Ginseng on the Symptoms of depression and anxiety in Drug users

Comparing the effectiveness of ginseng on the symptoms of depression and anxiety in drug users

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240310061238N1

Enrollment

Registered

2024-04-10

Start date

2024-07-05

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Anxiety. Condition 2: Anxiety. Anxiety disorder, unspecified Unspecified mood [affective] disorder

Interventions

Intervention 1: Intervention group: Patients receive ginseng capsules (100 mg) . The intervention group received two ginseng capsules (100 mg) daily for four weeks. Intervention 2: Patients receive pl

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Drug users who are undergoing maintenance treatment with methadone and buprenorphine in the age range of 18 to 60 years will be included in the study. Drug-dependent patients for at least one year using fixed-dose drugs at least in the last month

Exclusion criteria

Exclusion criteria: Pregnant or lactating mothers Patients with other psychological problems (bipolar-schizophrenia-dementia or mental retardation) Concomitant serious medical diseases

Design outcomes

Primary

Measure	Time frame
Anxious mood score with Hamilton questionnaire criteria. Timepoint: Examining the anxiety score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;Depressed mood score with Hamilton questionnaire criteria. Timepoint: Examining the depression score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.	—

Measure

Time frame

Anxious mood score with Hamilton questionnaire criteria. Timepoint: Examining the anxiety score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;Depressed mood score with Hamilton questionnaire criteria. Timepoint: Examining the depression score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.

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Secondary

Measure	Time frame
Sleep disorder score with Hamilton questionnaire criteria. Timepoint: Examining the sleep disorder score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;Diminished ability to concentrate score with Hamilton questionnaire criteria. Timepoint: Examining the difficulty in concentration score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;General physical condition score with Hamilton questionnaire criteria. Timepoint: Examining the score of general physical symptoms with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.	—

Measure

Time frame

Sleep disorder score with Hamilton questionnaire criteria. Timepoint: Examining the sleep disorder score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;Diminished ability to concentrate score with Hamilton questionnaire criteria. Timepoint: Examining the difficulty in concentration score with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.;General physical condition score with Hamilton questionnaire criteria. Timepoint: Examining the score of general physical symptoms with the Hamilton questionnaire, at the beginning of the study (before the start of the intervention), and 14 and 28 days after receiving ginseng. Method of measurement: Hamilton anxiety and depression questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyede Fateme Mesbahi

Ahvaz University of Medical Sciences

fatememesbahi@yahoo.com+9861330383374

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026