Investigating the effect of high global quality of diet and artichoke supplement in non-alcoholic fatty liver disease

Investigating the simultaneous effect of high global diet quality score and standard diet with and without artichoke supplementation on fasting blood sugar, lipid profile and liver function indices in patients with non-alcoholic fatty liver disease: a randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240310061235N1

Enrollment

100

Registered

2024-06-20

Start date

2024-06-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with non-alcoholic fatty liver disease. Nonalcoholic fatty liver disease [NAFLD]

Interventions

Intervention 1: The first intervention group. Intervention 2: The second intervention group. Intervention 3: The third intervention group. Intervention 4: Control group:.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age above 18 years Suffering from non-alcoholic fatty liver grade 1-3

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding suffering from hepatitis, coronary, kidney, lung and thyroid diseases

Design outcomes

Primary

Measure	Time frame
Fatty liver grade. Timepoint: The beginning and end of the study. Method of measurement: Ultrasound machine.;Liver enzymes (ALT, AST). Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.;Fasting blood glucose. Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.;Lipid profile (LDL-c, HDL-c, TG). Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.	—

Measure

Time frame

Fatty liver grade. Timepoint: The beginning and end of the study. Method of measurement: Ultrasound machine.;Liver enzymes (ALT, AST). Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.;Fasting blood glucose. Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.;Lipid profile (LDL-c, HDL-c, TG). Timepoint: The beginning and end of the study. Method of measurement: Biochemical test.

—

Secondary

Measure	Time frame
Weight. Timepoint: The beginning and end of the study. Method of measurement: scale.;Waist. Timepoint: The beginning and end of the study. Method of measurement: tape measure.;Food intake. Timepoint: The beginning and end of the study. Method of measurement: 24-hour feed reminder.;Physical activity. Timepoint: The beginning and end of the study. Method of measurement: IPAQ questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMona Jamalvandi

Yazd University of Medical Sciences

m.jamalvandi71@yahoo.com+98 35 3820 9100

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026