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Evaluation of the effects of two doses of ursodeoxycholic acid on reducing gallstone formation

Evaluation of the effects of two doses of ursodeoxycholic acid by sonography on reducing gallstone formation after sleeve gastrectomy in female patients with class 3 obesity : a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240310061234N1
Enrollment
164
Registered
2025-05-26
Start date
2021-03-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gallstone. Gallstone ileus

Interventions

Intervention 1: Control group: They received Ursodeoxycholic acid tablets as 300 mg daily. Intervention 2: Intervention group: They received Ursodeoxycholic acid 300 mg twice daily.

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: All adult female individuals who have undergone sleeve gastrectomy referred to Loghman Hakim Hospital whom their information was available for 1 year. Patients who were consent to participate in study.

Exclusion criteria

Exclusion criteria: Female adults who were not consent to participate in study. Age < 15 years. Any adverse effect or allergy to Ursodeoxycholic Acid. Previous Cholecystectomy. Missing patient information or patient unavailability. Mental or physical diseases.

Design outcomes

Primary

MeasureTime frame
Gallstone formation. Timepoint: Weight loss data of patients will be recorded monthly. At the end of six months, abdominal ultrasound for gallstones is performed in patients and the results are analyzed. Method of measurement: Abdominal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Shishvan

Shahid Beheshti University of Medical Sciences

Sa_sh1983@yahoo.com+98 21 8824 4806

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026