Poisoning. Other opioids
Conditions
Interventions
Intervention 1: Intervention group: Vitamin C100- 200 mg/kg body weight is administered intravenously along with standard treatment of acute liver failure. Intervention 2: Control group:The second gro
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Informed written consent to enter the investigation on behalf of the patient or legal guardian. Age between 18 and 65 years old. Patients without chronic underlying conditions such as liver and kidney disease, autoimmune disease or cancers Patients do not have acute kidney injury Patients do not have G6PD Deficiency Opioid poisoning hospitalized that the amount of liver enzymes is more than 5 times higher It is normal.
Exclusion criteria
Exclusion criteria: Lack of written consent from the patient or legal guardian to enter the investigation Any chronic underlying diseases such as liver and kidney disease, autoimmunity, or cancers. No acute kidney injury. 0No G6PDDefficiency Age outside the range of 18-65 years.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase serum levels of liver enzymes following opioid abuse. Timepoint: The serum levels of liver enzymes of the patients are measured daily after enrollment in the study from the first day. Method of measurement: laboratory kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNegin Alsadat Sadeghi
Islamic Azad University
Outcome results
None listed