The response of a single bout of resistance training with different intensity and recovery on inflammatory and pro-inflammatory factors in female bodybuilders

The response of a resistance activity with different intensity and recovery in gene expression of Nf-kB, IL-6, TNF-a and serum comparison ACTH, hsp-70, CBC-diff in female bodybuilders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240305061178N1

Enrollment

Registered

2024-03-29

Start date

2023-11-11

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The formation of pro-inflammatory and inflammatory markers in blood serum due to resistance training.

Interventions

Intervention group: Intervention group: There was only one intervention group, which was a one-time resistance training intervention. The training program was as follows: the training protocol was des

Eligibility

Sex/Gender

Female

Age

25 Years to 42 Years

Inclusion criteria

Inclusion criteria: A history of at least two years of bodybuilding that has not used drugs, supplements, alcohol or cigarettes in the last six months

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
The independent variable will be checked on the following dependent variables:Moderate and high intensity resistance trainingThe independent variables include the following:Pro-inflammatory factors:TNF-a, IL6Anti-inflammatory factors:BDNF, HSP70 and ACTHand inflammatory clinical indicators:CRP, CBC-diffAnd also the inflammatory signaling pathway factor:nF-kB. Timepoint: 36 hours after resistance training with specific intensity and recovery. Method of measurement: The collection tool of this research is through blood sampling and laboratory equipment. The measurement of corticotropin is using the ELISA method. H9648 human adrenocorticotropic hormone, ACTH ELISA Kit=ZB-1032-H9648 Human Tumor Necrosis Factor-a ELISA Kit Human NF-?B ELISA kit.	—

Measure

Time frame

The independent variable will be checked on the following dependent variables:Moderate and high intensity resistance trainingThe independent variables include the following:Pro-inflammatory factors:TNF-a, IL6Anti-inflammatory factors:BDNF, HSP70 and ACTHand inflammatory clinical indicators:CRP, CBC-diffAnd also the inflammatory signaling pathway factor:nF-kB. Timepoint: 36 hours after resistance training with specific intensity and recovery. Method of measurement: The collection tool of this research is through blood sampling and laboratory equipment. The measurement of corticotropin is using the ELISA method. H9648 human adrenocorticotropic hormone, ACTH ELISA Kit=ZB-1032-H9648 Human Tumor Necrosis Factor-a ELISA Kit Human NF-?B ELISA kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAZAR MOMTAZ

Islamic Azad University

AZAR.MOMTAZ@GMAIL.COM+98 13 3450 5093

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026