Immunomodulatory effect on healthy volunteers.
Conditions
Interventions
Intervention 1: Intervention group: healthy volunteers take Byolic CC capsules produced by Behpad Tab for 2 months, once a day, preferably with meals. Intervention 2: Control group: healthy volunteers
Sponsors
Behpad Teb Iranian
Shahed university Immune Response Regulation Research Center
Eligibility
Sex/Gender
All
Age
15 Years to 60 Years
Inclusion criteria
Inclusion criteria: Health of volunteers
Exclusion criteria
Exclusion criteria: usage of immunosuppressive drugs, including cytotoxic drugs and corticosteroids, or any other drug (within 4 weeks before the start of the study) that may interfere with the supplement used in this study (or other herbal products) drug and food allergies pregnancy and lactation cardiovascular, kidney, lung, liver, endocrine, hematological, neurological or psychiatric diseases, etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety check variables:Physical examination, vital signs and laboratory measurements including blood biochemistry (BC) and complete blood count (CBC). Timepoint: Day 0,30,60. Method of measurement: Physical examination, Blood test.;Variables for investigating the immunomodulatory effect: Measuring the levels of cytokines TNF-a and IL-12 in serum samples by ELISA method, Measuring the level of cytokine IFN-? in the supernatant, Measuring the proliferation and activation of NK cells by flow cytometry using FITC-a-human CD56 and PE-a-human CD314 (NKG2D) antibodies. Timepoint: Day 0 and 60. Method of measurement: Serum sample analyze. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAzade Rashidi
Immunoregulation Research Center
Outcome results
None listed