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Effect of Intrasocket Application of Hyaluronic Acid

Comparison of Intrasocket Application of Hyaluronic Acid+Gelfoam Vs Gelfoam Alone to Reduce Post-Operative Pain and Trismus after Surgical Extraction of Lower Wisdom Teeth

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240301061136N1
Enrollment
15
Registered
2024-03-28
Start date
2024-09-01
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative pain and trismus (mouth opening).

Interventions

Intervention 1: Intervention group: this is the site of surgical extraction which will receive Hyaluronic acid+ Gelfoam within the socket. 1.7ml of 20mg/2ml Hyaluronic Acid will be used (Hylagun prefi

Sponsors

CMH Lahore Medical College and Institute of Dentistry
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 18-40 years of age Do not have any systemic disease Non-smoker, Non-alcoholic symmetrically impacted third molars on both sides of the mandible Require surgical extraction of impacted teeth Similar difficulty level on both sides according to Pederson scale Gave consent for participation

Exclusion criteria

Exclusion criteria: systolic blood pressure (>140 mmHg,90mmHg , <60mmHg). Any history of allergy or adverse effects to antibiotics, analgesics, or local anesthetics Acute infection such as pericoronitis and/or complication or pain on the impaction area before extraction Any physical or mental disability Pregnant woman and any use of contraceptives or corticosteroids which can affect the postsurgical complication of healing and amount of swelling on the face Tobacco use in any form Any patient taking antibiotics and analgesics for 15 days before operation Taken antidepressants 5 days before the surgery Non-cooperative patient

Design outcomes

Primary

MeasureTime frame
Pain and trismus. Timepoint: 1st 2nd and 7th post operative day. Method of measurement: Pain measured through NRS and Trismus is the Inter-incisal distance measured in mm using a ruler.

Secondary

MeasureTime frame
Dry socket and painkiller use. Timepoint: 3rd 4th and 7th post operative day. Method of measurement: Visual assessment of dry socket symptoms. Painkiller use measured by the number of tablets used post operatively.

Countries

Pakistan

Contacts

Public ContactDr. Rida Binte Zahid

CMH Lahore Medical College and Institute of Dentistry

ridabintezahid@gmail.com+92 42 35929717

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026