Investigating the effect of intravenous tranexamic acid in reducing the bleeding volume of acute burn surgical debridement

The effect of intravenous tranexamic acid in reducing the volume of bleeding after debridement of acute burn wounds

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240301061135N1

Enrollment

Registered

2024-03-12

Start date

2024-04-03

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of intravenous tranexamic acid in reducing bleeding volume after surgical debridement of acute burn wounds.

Interventions

Intervention 1: Intervention group: patients receive tranexamic acid 10 mg/kg. Intervention 2: Control group: patients receive 10 ml of normal saline.

Eligibility

Sex/Gender

All

Age

15 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with thermal burns less than 30% of the body surface who are candidates for surgical debridement of acute burn wounds.

Exclusion criteria

Exclusion criteria: Patients with chemical burns Patients with history or susceptibility to thrombosis Patients with a history of sensitivity to tranexamic acid Patients with subarachnoid hemorrhage Patients with renal dysfunction Pregnancy Breastfeeding

Design outcomes

Primary

Measure	Time frame
The volume of blood lost during surgical debridement of burn wounds. Timepoint: During surgery. Method of measurement: Hemoglobin before and after the operation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Javadi

Iran University of Medical Sciences

drmajidjavadips@gmail.com+98 21 8871 7272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026