Burn wound.
Conditions
Interventions
Intervention 1: Intervention group: . For the patients in the intervention group, the gauze dressing will be soaked in 500 mg diluted tranexamic acid plus 1 mg norepinephrine diluted in 500 ml 0.9% sa
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 55 Years
Inclusion criteria
Inclusion criteria: patients between 15-55 years old over than 20 percent surface of body need skin debridement
Exclusion criteria
Exclusion criteria: dont need icu care not to be third grade burn dont have chemical or electrical burn dont have blunt abdominal trauma or head trauma dont have bleeding disorders dont have thrombotic disorders or hypercoagulopathy dont be post partum or pregnant Hypersensitivity to tranexamic acid Systolic blood pressure higher than 200 mmHg Disruption of coagulation factors Have disturbances in kidney function tests
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin level. Timepoint: Complete blood count test before operation and 24 hours after operation. Method of measurement: Complete blood count test through the patient's blood sample.;Hematocrit level. Timepoint: Complete blood count test before operation and 24 hours after operation. Method of measurement: Complete blood count test through the patient's blood sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| Occurrence of possible side effects. Timepoint: From the time the patient arrives to the time of discharge from the hospital. Method of measurement: Investigating the presence of side effects during hospitalization.;Duration of hospital stay. Timepoint: The time of arrival to the departure of the patient from the hospital. Method of measurement: Number of days of hospitalization.;The number of Pack cell received. Timepoint: After surgery. Method of measurement: The number of cell packs. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Esmaielzadeh
Karaj University of Medical Sciences
Outcome results
None listed