Apraxia of Speech resulting from stroke. Apraxia following cerebral infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: History of a stroke in the dominant hemisphere for the language that has been at least 6 months since its occurrence Be monolingual Persian Passing the Pure Tone Audiometry Screening test at the threshold of 35 dB at frequencies of 500, 1000, and 2000 for at least one ear; if the patient uses a hearing aid, it is necessary to confirm the hearing adequacy at the conversational level by an audiologist Normal or corrected (using lenses or glasses) visual ability Absence of alcohol or drug abuse, psychological and neurological disorders other than stroke based on self-report and confirmation by their medical records Obtaining a normal range score of the non-verbal intelligence test using Raven's progressive matrices Being right-handed by Edinburgh handedness questionnaire Absence of dysarthria or mild dysarthria according to the Frenchay Dysarthria Assessment 2 (FDA-2) Auditory comprehension above 50% in Persian Mississippi Aphasia Screening Test (MASTp) and Persian Diagnostic Aphasia Battery (P-DAB-1) Has a literacy level of 8th grade and above Diagnosis as AOS based on supplemental verbal apraxia test Obtaining a minimum score of 32 (moderate severity) and above in the verbal apraxia test
Exclusion criteria
Exclusion criteria: History of more than a stroke in the dominant hemisphere for the language 6 months have not passed since the stroke Not passing the Pure Tone Audiometry Screening test at the threshold of 35 dB at frequencies of 500, 1000, and 2000 for at least one ear Failure to confirm hearing adequacy at the conversational level by an audiologist Absence of normal vision or inability to correct defective vision using lenses or glasses History of alcohol or drug abuse, psychological and neurological disorders other than stroke based on self-report and confirmation by medical records Not obtaining a normal range score of the non-verbal intelligence test using Raven's progressive matrices Not being right-handed, according to the Edinburgh Handedness Questionnaire Having dysarthria above mild severity according to the Frenchay Dysarthria Assessment 2 (FDA-2) test Not to be achieved auditory comprehension above 50% in the Persian Mississippi Aphasia Screening Test (MASTp) and the Persian Diagnostic Aphasia Battery (P-DAB-1) Has a literacy level lower than 8th grade Not diagnosing as AOS based on supplemental verbal apraxia test Obtaining a score of lower than 32 in the verbal apraxia test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trained words and phrases accuracy. Timepoint: Continuous assessments in probe sessions in baseline, treatment and following phases. Method of measurement: Percentage of accurate words and phrases.;Un-trained words and phrases accuracy. Timepoint: Continuous assessments in probe sessions in baseline, treatment and following phases. Method of measurement: Percentage of accurate words and phrases.;Percentage of Consonants Correct in trained words and phrases. Timepoint: Continuous assessments in probe sessions in baseline, treatment, and following phases. Method of measurement: The number of consonants produced correctly in the trained words and phrases is divided by the total number of consonants and expressed as a percentage.;Percentage of Consonants Correct (PCC) in un-trained words and phrases. Timepoint: Continuous assessments in probe sessions in baseline, treatment and following phases. Method of measurement: The number of consonants produced correctly in the un-trained words and phrases is divided by the total number of consonants and expressed as a percentage.;Percentage of Vowels Correct (PVC) in trained words and phrases. Timepoint: Continuous assessments in probe sessions in baseline, treatment and following phases. Method of measurement: The number of vowels produced correctly in the trained words and phrases is divided by the total number of consonants and expressed as a percentage.;Percentage of Vowels Correct (PVC) in un-trained words and phrases. Timepoint: Continuous assessments in probe sessions in baseline, treatment and following phases. Method of measurement: The number of vowels produced correctly in the un-trained words and phrases is divided by the total number of consonants and expressed as a percentage. | — |
Secondary
| Measure | Time frame |
|---|---|
| Type of aphasia. Timepoint: Before starting the baseline and after completing the treatment phase. Method of measurement: Based on comprehension and expression scores by The Persian version of the Mississippi Aphasia Screening Test (MASTp).;Aphasia severity. Timepoint: Before starting the baseline and after completing the treatment phase. Method of measurement: Based on Persian Diagnostic Aphasia Battery (P-DAB-1) score.;Apraxia of Speech severity. Timepoint: Before starting the baseline and after completing the treatment phase. Method of measurement: Based on verbal apraxia tasks for adults score.;Intelligibility in words and sentences. Timepoint: Before starting the baseline and after completing the treatment phase. Method of measurement: Based on speech intelligibility of Frenchay Dysarthria Assessment (FDA - 2).;Percentage of Consonant Correct in producing words and spontaneous speech. Timepoint: Before starting the baseline and after completing the treatment phase. Method of measurement: Based on phonetic information test and spontaneous speech sample. | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences