knee osteoarthritis. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: First intervention group: in the first group, treatment is done with a platelet-rich plasma injection, so that 20 CC of blood is taken from the patient and centrifuged in the first rou
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients based on ACR (American college of rheumatology) radiological criteria with knee Grade I, II and III osteoarthritis
Exclusion criteria
Exclusion criteria: Patients who are breastfeeding or pregnant They have rheumatoid arthritis or severe heart disease. Have a skin infection at the injection site Be a consumer of immunosuppressive drugs or anticoagulants such as warfarin and heparin A history of bleeding or a description of clotting disorders or anemia Have current back pain with spreading to lower limbs Have a history of knee surgery in the last three months Have an active infection or malignancy within the previous 6 months Substance abuse Intra-articular corticosteroid injections in the last 2 months or hyaluronic acid in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A comparative study of the effects of platelet-rich plasma, platelet-rich fibrin and prednisolone injections in the treatment of knee arthrosis. Timepoint: Evaluation of patients before intervention begins and 1, 3 and 6 months after injection. Method of measurement: Vas criteria, WOMAC questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparative study of the effects of platelet-rich plasma injections and platelet-rich fibrin and prednisolone on reducing stiffness in knee osteoarthritis. Timepoint: Before the start of the intervention and then 1, 3 and 6 months after the injection. Method of measurement: WOMAC questionnaire.;Comparative study of the effects of platelet-rich plasma injections and platelet-rich fibrin and prednisolone on daily functioning of patients with knee osteoarthritis. Timepoint: Before the start of the intervention and then 1, 3 and 6 months after the injection. Method of measurement: WOMAC questionnaire.;Comparative study of the effects of platelet-rich plasma injections and platelet-rich fibrin and prednisolone on reducing pain in knee osteoarthritis. Timepoint: Before the start of the intervention and then 1, 3 and 6 months after the injection. Method of measurement: VAS criteria. WOMAC questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShiva Mohammad alizadeh
Tehran University of Medical Sciences
Outcome results
None listed