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The effect of diclofenac suppository on post-cesarean section hemorrhage

Evaluation of the effect of diclofenac suppository on post-cesarean section hemorrhage

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240221061071N1
Enrollment
88
Registered
2024-10-12
Start date
2024-10-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-cesarean section hemorrhage.

Interventions

Intervention 1: Intervention group: 50mg Diclofenac rectal suppository preoperatively and every 6 hours to 24 hours. Intervention 2: Control group: 50mg placebo rectal suppository manufactured by phar

Sponsors

Alborz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Singleton pregnancy Age 18 to 45 years Gestational age = 34 weeks Caesarean section candidate with previous cesarean history Prenatal hemoglobin level in the week before caesarean section> 90 g/L ASA=II.

Exclusion criteria

Exclusion criteria: Placenta previa Invasive abnormal placenta Eclampsia syndrome Hemolysis with low platelets Uterine Fetal Death Unsuccessful operative vaginal delivery Multiple pregnancies Severe polyhydramnios Uterine fibroids Recurrent abortion History of Coagulation Disorders, Liver disease and Renal disfunction History of Gastrointestinal bleeding or peptic ulcer Asthma Drug allergy Use of anticoagulants, anti -platelets, NSAIDs and corticosteroids History of epilepsy or seizures

Design outcomes

Primary

MeasureTime frame
The amount of bleeding. Timepoint: Before surgery and 6 and 24 hours after surgery. Method of measurement: Measurement of hemoglobin and hematocrit and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Sayyede Ala Hajihosseini

Alborz University of medical sciences

a.hajihosseini@abzums.ac.ir+98 26 3224 0014

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026