Pain after surgery. Other acute postprocedural pain
Conditions
Interventions
Intervention 1: Intervention group: methadone intramuscularly at a dose of 5 mg every 8 hours. Concentration: 5 milligrams per milliliter (5 mg/mL). Depending on the severity of the pain, this inter
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients who underwent cervical spine surgery Age between 18 and 90 years old Obtained Written informed consent
Exclusion criteria
Exclusion criteria: Allergy or hypersensitivity to methadone or morphine patient's hesitancy or refusal for participation in the study Psychologic disorders Use of drugs that affect methadone metabolism QT length >440ms in ECG Serum levels of K35
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of the pain. Timepoint: 0, 2, 4, 8, 12, 24 hours after surgery. Method of measurement: Visual Analogue Scale.;Pain severity. Timepoint: 0, 2, 4, 8, 12, 24 hours after surgery. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Vital signs including heart rate, respiratory rate, systolic and diastolic blood pressure. Timepoint: 0, 2, 4, 8, 12, 24 hours after surgery. Method of measurement: Vital sing monitoring equipment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMilad Masaeli
Esfahan University of Medical Sciences
Outcome results
None listed