comparison dexamethasone and meperidine on shivering

A comparative study of the prophylactic effect of intravenous dexamethasone and meperidine on shivering in patients undergoing cesarean section with spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240221061070N1

Enrollment

Registered

2024-04-15

Start date

2024-02-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post surgical shivering. Complication of anesthesia during labor and delivery, unspecified

Interventions

Intervention 1: Intervention group: first.2 milligram intra venous dexamethasone in un specified 2 cc syringe. From 8 mgr vial of Dexamethasone and single injection. Intervention 2: Intervention group

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: pregnant women ASA Class 1-2 Elective cesarean

Exclusion criteria

Exclusion criteria: cardiac disease pulmonary disease liver disease renal disease psychological disease diabetes mellitus thyroid disease body temperature less than 36.5 Celsius degree body temperature more than 38.5 Celsius degree history of alcohol abuse history of drug abuse intra operative blood transfusion analgesic drugs administration take any drugs effect on body temperature

Design outcomes

Primary

Measure	Time frame
Shivering incidence. Timepoint: 0,5,10,15,30,45,60,90(min). Method of measurement: Based on shivering in the patient based on the patient's expression or muscle contraction.;Shivering severity. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Zero degree: no shivering, Grade 1: Peripheral vasoconstriction, but without visible shivering. Second degree: muscle activity in only one muscle group. Grade 3: Muscle activity in more than one muscle group, but not generalized. Fourth degree: trembling that involves the whole body.	—

Measure

Time frame

Shivering incidence. Timepoint: 0,5,10,15,30,45,60,90(min). Method of measurement: Based on shivering in the patient based on the patient's expression or muscle contraction.;Shivering severity. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Zero degree: no shivering, Grade 1: Peripheral vasoconstriction, but without visible shivering. Second degree: muscle activity in only one muscle group. Grade 3: Muscle activity in more than one muscle group, but not generalized. Fourth degree: trembling that involves the whole body.

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Secondary

Measure	Time frame
Blood pressures. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Non invasive couphmetr.;Room temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: E.SUN thermometer.;Core temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: In the inner ear area (using the tympanic membrane thermometer, which is considered the average core temperature and the GENTLE TEMP 520 thermometer from OMRON company).	—

Measure

Time frame

Blood pressures. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Non invasive couphmetr.;Room temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: E.SUN thermometer.;Core temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: In the inner ear area (using the tympanic membrane thermometer, which is considered the average core temperature and the GENTLE TEMP 520 thermometer from OMRON company).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Masaeli

Esfahan University of Medical Sciences

drmilmas@gmail.com+98 31 3236 7001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026