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Evaluating the clinical efficacy of Apixaban vs. Warfarin in patients with cerebral venous thrombosis (CVT)

Evaluating the clinical efficacy of Apixaban vs. Warfarin in patients with cerebral venous thrombosis (CVT)

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240217061039N1
Enrollment
74
Registered
2024-05-16
Start date
2024-04-09
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral venous thrombosis. Cerebral infarction due to cerebral venous thrombosis, nonpyogenic

Interventions

Intervention 1: Intervention group: Intervention group: Standard treatment is given by injecting intravenous heparin or sub-cutaneous enoxaparin (at a dose of 1 mg per kg) twice a day for 5-10 days. A

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over 18 years of age who are diagnosed with CVT in imaging

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Evaluating the clinical efficacy of Apixaban vs. Warfarin in patients with cerebral venous thrombosis. Timepoint: 6 months. Method of measurement: Clinical efficacy is measured by calculating the 6-months MRS and the rate of recanalization. Drug side effects are also studied by examining the rate of major bleeding and recurrence of thrombosis.

Secondary

MeasureTime frame
Comparison of the relationship between 6-months MRS-recanalization-the rate of recurrence of thrombosis and major bleeding with age-sex and each of the risk factors between two drug groups. Timepoint: 6 months. Method of measurement: The relationship of each case of 6-months MRS- recanalization- recurrence of thrombosis and major bleeding with age- sex and each of the risk factors between the two drug groups of apixaban and warfarin is measured.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAfarin Ahmadian

Ahvaz University of Medical Sciences

frn.ahmadian@gmail.com+98 61 3374 3001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026