Glaucoma. Primary open-angle glaucoma
Conditions
Interventions
Intervention 1: Intervention group 1: For group 1, brimonidine is administered sublingually every 8 hours for 4 weeks, and the next visit time (4 weeks later
that is, 1 week more than the drug washout) is determined. In the second visit, the initial intraocular pressure is measured and recorded, and a water drinking test is performed for the patient. Then,
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with ocular hypertension (ocular HTN) (intraocular pressure above 21 mm Hg) Patients with early stages of early open-angle glaucoma (early POAG)
Exclusion criteria
Exclusion criteria: Patients with bradycardia Patients with a history of heart disease Patients with hypotension
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure. Timepoint: 4, 8 and 12 weeks. Method of measurement: Goldman Tonometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systemic complications, local complications. Timepoint: 4, 8 and 12 weeks. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Mohammadzadeh
Shahid Beheshti University of Medical Sciences
Outcome results
None listed