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Title : Investigating the effect of Tribulus Terrestris on improving the SSRI induced sexual dysfunction of patients suffering from depression: a randomized clinical trial.

Title : Investigating the effect of Tribulus Terrestris on improving the SSRI induced sexual dysfunction of patients suffering from depression: a randomized clinical trial.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240213060994N1
Enrollment
50
Registered
2024-06-23
Start date
2024-07-22
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

People with major depressive disorder treated with SSRIs who experience sexual dysfunction.. Other psychoactive substance use, unspecified with psychoactive substance-induced sexual dysfunction

Interventions

Intervention 1: Intervention group: In the intervention group with Tribulus Terrestris, the patients will consume Greensol tablets containing 500 mg of powder dry extract of the fruit of thistle plant

Sponsors

Shahre-kord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age 20 to 50 years 2. At least two months of SSRI treatment have passed 3. According to the BDI (Beck Depression Questionnaire) score, they are not currently depressed (Beck Questionnaire score less than 14). 4. Have not previously received treatment for sexual dysfunction 5. Satisfied with sexual function before starting SSRI or depression

Exclusion criteria

Exclusion criteria: Menopause symptoms Taking psychiatric drugs or drugs to enhance sexual performance during the study pregnancy Concomitant medical or psychiatric illness that causes sexual dysfunction

Design outcomes

Primary

MeasureTime frame
A score higher than 51 in Larson's sexual satisfaction questionnaire; A score of less than 18 on the Arizona Sexual Experience Questionnaire. Timepoint: Measuring sexual satisfaction and sexual experience before the intervention, one and two months after the intervention will be used. Method of measurement: To measure the level of sexual satisfaction, the Larson questionnaire and the Arizona sexual satisfaction questionnaire will be used.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Zarean

Shahre-kord University of Medical Sciences

e.zarean@skums.ac.ir+98 38 3333 0061

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026