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Investigating the effect of vitamin A ophthalmic ointment on reducing pain after refractive keratectomy surgery

Investigating the effect of vitamin A ophthalmic ointment on reducing pain and accelerating the recovery of corneal abrasions after photorefractive keratectomy

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240213060989N1
Enrollment
56
Registered
2024-03-04
Start date
2024-02-29
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain reduction after Photorefractive keratectomy surgery.

Interventions

Intervention 1: control group: In these patients, routine drugs such as chloramphenicol, betamethasone and artificial tears are used randomly in one eye every 8 hours for a month. Intervention 2: Inte

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Class I and II of the American Society of Anesthesiology People with refractive error myopia and regular astigmatism (both together or each one alone) The optical amount of the zone is 5.6 - 5.7 People with spherical equivalent maximum 3.5 diopters

Exclusion criteria

Exclusion criteria: Lack of consent to participate in the study Use of contact lenses in the last two months Presence of corneal scratch before surgery taking medication Corneal dystrophies The presence of any structural disorder of the eye Pathology and eye diseases Existence of systemic diseases (diabetes, vascular collagen disorder, etc.) People with hyperopia, amblyopia

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS). Timepoint: Immediately after the operation, 6, 12 and 24 hours. Method of measurement: It will be quantitatively recorded from 0 (no pain) to 5 (very intense pain that is excruciating).

Secondary

MeasureTime frame
Corneal scratch. Timepoint: Examination by hand-held slit lamp In the daily visits after the surgery (until the complete recovery of the corneal scratch) and then a re-visit will be done one week after the surgery. Method of measurement: Based on mm.;Time of onset of first pain. Timepoint: Based on the patient condition checklist. Method of measurement: Time of onset of first pain after surgery.;Patient's eye complaint. Timepoint: Based on the patient condition checklist. Method of measurement: subjectively and comparing binoculars.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Hajizadeh

Ahvaz University of Medical Sciences

hajizadeh-m@ajums.ac.ir+98 916 131 3548

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026